Current Trials

We are currently running studies across a range of therapeutic areas including respiratory, neurology and cardiovascular disease.

 

Contact us to find out more d-icb.research.l83048@nhs.net

 

Some examples of our Non- Commercial studies:-

OPEN BUT NOW CLOSED TO RECRUITMENT 

 

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Active Brains is an interactive website for people aged 60-85 designed to help with lifestyle changes and brain training activities that can help to keep the brain and body healthy. The study you have been invited to take part in is to test if Active Brains works.

 

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BEACON is an online clinical trial for people with Long Covid who are experiencing brain fog or having problems with their memory and brain health

 

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PRINCIPLE is a UK-wide clinical study from the University of Oxford to find COVID-19 treatments for recovery at home.

 

Our current Commercial Studies:-

OPEN BUT NOW CLOSED TO RECRUITMENT 

 

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About the TRAILRUNNER-ALZ 3 Study

The TRAILRUNNER-ALZ 3 Study is evaluating an investigational medicine to see if it can help treat people with early Alzheimer’s disease.
Learn more about the TRAILRUNNER-ALZ 3 Study here. Brochure for Trailrunner ALZ 3 Stud

About the TRAILRUNNER-ALZ 3 Study

The TRAILRUNNER-ALZ 3 Study will see if an investigational medicine can help treat people with early Alzheimer’s disease.

You may be able to take part in this study if you:

  • Are aged 65 to 80 years old
  • Have no to mild issues with your memory
  • Are willing to obtain a blood test as part of the study that checks whether you have an abnormal protein association with Alzheimer’s disease
  • Have a reliable study partner*

 

*A study partner is a person who knows you well and would notice any changes in your memory, mood, or behavior. This could be your spouse, partner, friend, family memory, or someone whose job it is to help you. Your study partner would also need to consent to participate in the research study.

 

If you are interested in participating, the study doctor and staff will review additional eligibility criteria with you.

 

Study Overview

If you qualify to take part in the TRAILRUNNER-ALZ 3 Study, you will be randomly (that is by chance) assigned to either the investigational medicine group or the placebo group. For every 2 study participants, 1 will get investigational medicine and 1 will get placebo.

You will get an injection under the skin using a prefilled syringe. The first 5 doses will be at the clinic. The study team will give you these injections and show you how to do this. You or your study partner can give you the remaining injections at a convenient location, like at home, or you can go to the clinic. If your study partner is helping you, the study team will also show them how to give the injections.

This study will last about 5 years. It has 5 parts, including an optional extension to the study treatment period for eligible participants. After the observation period, if the investigational medicine is safe and effective, participants who received placebo may take part in the extension period and get investigational medicine. The study team will explain this to you in more detail.

During the study you will attend visits with doctors and researchers in-person at a clinic.

Your study partner should come to study visits with you. If they cannot come to a visit, they should be available by phone for any questions or follow-up. They must be able to tell the research team about any changes in your memory and thinking.